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3D scaffold-free microlivers with drug metabolic function generated by lineage-reprogrammed hepatocytes from human fibroblasts.

Lu Z, Priya Rajan SA, Song Q, Zhao Y, Wan M, Aleman J, Skardal A, Bishop C, Atala A, Lu B
Biomaterials. 2021 Feb;269:120668. doi: 10.1016/j.biomaterials.2021.120668. Epub 2021 Jan 8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
149724pLV-HNF4A-FOXA2-FOXA3expressing three liver promoting transcription factors (HNF4A, FOXA2, FOXA3)
149725pLV-ATF5-PROX1-HNF1Aexpressing three liver promoting transcription factors (ATF5, PROX1, HNF1A)

Antibodies from Article