Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.

Koenig PA, Das H, Liu H, Kummerer BM, Gohr FN, Jenster LM, Schiffelers LDJ, Tesfamariam YM, Uchima M, Wuerth JD, Gatterdam K, Ruetalo N, Christensen MH, Fandrey CI, Normann S, Todtmann JMP, Pritzl S, Hanke L, Boos J, Yuan M, Zhu X, Schmid-Burgk JL, Kato H, Schindler M, Wilson IA, Geyer M, Ludwig KU, Hallberg BM, Wu NC, Schmidt FI
Science. 2021 Feb 12;371(6530). pii: science.abe6230. doi: 10.1126/science.abe6230. Epub 2021 Jan 12. PubMed Article

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No plasmids are currently publicly available from Addgene for this article.