Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion.
Scharping NE, Rivadeneira DB, Menk AV, Vignali PDA, Ford BR, Rittenhouse NL, Peralta R, Wang Y, Wang Y, DePeaux K, Poholek AC, Delgoffe GM
Nat Immunol. 2021 Feb;22(2):205-215. doi: 10.1038/s41590-020-00834-9. Epub 2021 Jan 4.
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