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The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s.

Tunbak H, Enriquez-Gasca R, Tie CHC, Gould PA, Mlcochova P, Gupta RK, Fernandes L, Holt J, van der Veen AG, Giampazolias E, Burns KH, Maillard PV, Rowe HM
Nat Commun. 2020 Nov 3;11(1):5387. doi: 10.1038/s41467-020-19170-5. (Link opens in a new window) PubMed (Link opens in a new window) Article

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