A novel kinase inhibitor, LZT-106, downregulates Mcl-1 and sensitizes colorectal cancer cells to BH3 mimetic ABT-199 by targeting CDK9 and GSK-3beta signaling.

Yu Z, Du J, Zhao Y, Gao Y, Li Y, Zhao K, Lu N
Cancer Lett. 2021 Feb 1;498:31-41. doi: 10.1016/j.canlet.2020.10.001. Epub 2020 Oct 28. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.