Next-generation GRAB sensors for monitoring dopaminergic activity in vivo.
Sun F, Zhou J, Dai B, Qian T, Zeng J, Li X, Zhuo Y, Zhang Y, Wang Y, Qian C, Tan K, Feng J, Dong H, Lin D, Cui G, Li Y
Nat Methods. 2020 Nov;17(11):1156-1166. doi: 10.1038/s41592-020-00981-9. Epub 2020 Oct 21.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 140553 | pAAV-hsyn-GRAB_DA2m | Expresses the 2nd generation medium-affinity DA sensor GRAB_DA2m in neurons |
| 140554 | pAAV-hsyn-GRAB_DA2h | Expresses the 2nd generation high-affinity DA sensor GRAB_DA2h in neurons |
| 140555 | pAAV-hsyn-GRAB_DA-mut | Expresses the DA-insensitive control sensor GRAB_DA-mut in neurons |
| 140556 | pAAV-hsyn-GRAB_rDA1m | Expresses the red fluorescent medium-affinity DA sensor GRAB_rDA1m in neurons |
| 140557 | pAAV-hsyn-GRAB_rDA1h | Expresses the red fluorescent high-affinity DA sensor GRAB_rDA1h in neurons |
| 140558 | pAAV-hsyn-GRAB_rDA-mut | Expresses the red fluorescent DA-insensitive control sensor GRAB_rDA-mut in neurons |