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A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone.

Chen CD, Rudy MA, Zeldich E, Abraham CR
FASEB J. 2020 Jun;34(6):7234-7246. doi: 10.1096/fj.202000171R. Epub 2020 Apr 29. (Link opens in a new window) PubMed (Link opens in a new window) Article

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