HIV and opiates dysregulate K(+)- Cl(-) cotransporter 2 (KCC2) to cause GABAergic dysfunction in primary human neurons and Tat-transgenic mice.
Barbour AJ, Hauser KF, McQuiston AR, Knapp PE
Neurobiol Dis. 2020 Jul;141:104878. doi: 10.1016/j.nbd.2020.104878. Epub 2020 Apr 25.
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