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Gasdermin E suppresses tumour growth by activating anti-tumour immunity.

Zhang Z, Zhang Y, Xia S, Kong Q, Li S, Liu X, Junqueira C, Meza-Sosa KF, Mok TMY, Ansara J, Sengupta S, Yao Y, Wu H, Lieberman J
Nature. 2020 Mar;579(7799):415-420. doi: 10.1038/s41586-020-2071-9. Epub 2020 Mar 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
154876pLVX-Puro-hGSDMEExpresses hGSDME in mammalian cells
154877pLVX-Puro-mGSDMEExpresses mGSDME in mammalian cells
154878pLVX-Puro-mGSDME F2AExpresses mGSDME F2A in mammalian cells
223518pLVX-puro-mGSDME D270AExpresses mGSDME D270A in mammalian cells
223519pLentiCRISPR v2 puro hGSDME gRNA1knocking out hGSDME in human cells
223520pLentiCRISPR v2 puro hGSDME gRNA2Knocking out hGSDME in human cells

Antibodies from Article