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The apparent deglycase activity of DJ-1 results from the conversion of free methylglyoxal present in fast equilibrium with hemithioacetals and hemiaminals.

Andreeva A, Bekkhozhin Z, Omertassova N, Baizhumanov T, Yeltay G, Akhmetali M, Toibazar D, Utepbergenov D
J Biol Chem. 2019 Dec 6;294(49):18863-18872. doi: 10.1074/jbc.RA119.011237. Epub 2019 Oct 24. (Link opens in a new window) PubMed (Link opens in a new window) Article

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