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Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC.

Wei L, Lee D, Law CT, Zhang MS, Shen J, Chin DW, Zhang A, Tsang FH, Wong CL, Ng IO, Wong CC, Wong CM
Nat Commun. 2019 Oct 15;10(1):4681. doi: 10.1038/s41467-019-12606-7. (Link opens in a new window) PubMed (Link opens in a new window) Article

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