Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning.

Wang D, Zhang C, Wang B, Li B, Wang Q, Liu D, Wang H, Zhou Y, Shi L, Lan F, Wang Y
Nat Commun. 2019 Sep 19;10(1):4284. doi: 10.1038/s41467-019-12281-8. PubMed Article

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