SponGee: A Genetic Tool for Subcellular and Cell-Specific cGMP Manipulation.
Ros O, Zagar Y, Ribes S, Baudet S, Loulier K, Couvet S, Ladarre D, Aghaie A, Louail A, Petit C, Mechulam Y, Lenkei Z, Nicol X
Cell Rep. 2019 Jun 25;27(13):4003-4012.e6. doi: 10.1016/j.celrep.2019.05.102. PubMed Article
Ros O, Zagar Y, Ribes S, Baudet S, Loulier K, Couvet S, Ladarre D, Aghaie A, Louail A, Petit C, Mechulam Y, Lenkei Z, Nicol X
Cell Rep. 2019 Jun 25;27(13):4003-4012.e6. doi: 10.1016/j.celrep.2019.05.102. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 134775 | pCX-SponGee | mammalian expression of SponGee, a buffer of cGMP that prevents downstream signaling |
| 134776 | pCX-Lyn-SponGee | mammalian expression of Lyn-SponGee, a lipid raft-targeted variant of the cGMP buffer SponGee that prevents downstream signaling |
| 134777 | pCX-SponGee-Kras | mammalian expression of SponGee-Kras, a plasma membrane-targeted but lipid raft-excluded variant of the cGMP buffer SponGee that prevents downstream signaling |
| 134778 | pCX-ThPDE5VV | cGMP FRET biosensor |