A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system.
LaFleur MW, Nguyen TH, Coxe MA, Yates KB, Trombley JD, Weiss SA, Brown FD, Gillis JE, Coxe DJ, Doench JG, Haining WN, Sharpe AH
Nat Commun. 2019 Apr 10;10(1):1668. doi: 10.1038/s41467-019-09656-2. PubMed Article
LaFleur MW, Nguyen TH, Coxe MA, Yates KB, Trombley JD, Weiss SA, Brown FD, Gillis JE, Coxe DJ, Doench JG, Haining WN, Sharpe AH
Nat Commun. 2019 Apr 10;10(1):1668. doi: 10.1038/s41467-019-09656-2. PubMed Article
Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
113591 | pXPR_053 | Constitutive expression of a single sgRNA and the fluorophore violet-excited GFP in immune cells |