RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2.
Zhang Q, McKenzie NJ, Warneford-Thomson R, Gail EH, Flanigan SF, Owen BM, Lauman R, Levina V, Garcia BA, Schittenhelm RB, Bonasio R, Davidovich C
Nat Struct Mol Biol. 2019 Mar;26(3):237-247. doi: 10.1038/s41594-019-0197-y. Epub 2019 Mar 4. PubMed Article
Zhang Q, McKenzie NJ, Warneford-Thomson R, Gail EH, Flanigan SF, Owen BM, Lauman R, Levina V, Garcia BA, Schittenhelm RB, Bonasio R, Davidovich C
Nat Struct Mol Biol. 2019 Mar;26(3):237-247. doi: 10.1038/s41594-019-0197-y. Epub 2019 Mar 4. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 125161 | pFB1.HMBP.PrS.EZH2 | Expresses human EZH2 in insect cells, , under a C3-cleavable (PreScission Protease) N-terminal hexahistidine-MBP tag. |
| 125162 | pFB1.HMBP.PrS.SUZ12 | Expresses human SUZ12 in insect cells, , under a C3-cleavable (PreScission Protease) N-terminal hexahistidine-MBP tag. |
| 125163 | pFB1.HMBP.PrS.EED | Expresses human EED in insect cells, , under a C3-cleavable (PreScission Protease) N-terminal hexahistidine-MBP tag. |
| 125164 | pFB1.HMBP.PrS.RBBP4 | Expresses human RBBP4 in insect cells, , under a C3-cleavable (PreScission Protease) N-terminal hexahistidine-MBP tag. |
| 125165 | pFB1.HMBP.PrS.AEBP2 | Expresses human AEBP2 in insect cells, , under a C3-cleavable (PreScission Protease) N-terminal hexahistidine-MBP tag. |
| 125166 | pFB1.HMBP.PrS.JARID2 | Expresses human JARID2 in insect cells, , under a C3-cleavable (PreScission Protease) N-terminal hexahistidine-MBP tag. |
| 125167 | pFB1.HMBP.PrS.PHF1 | Expresses human PHF1 in insect cells, , under a C3-cleavable (PreScission Protease) N-terminal hexahistidine-MBP tag. |
| 125168 | pFB1.HMBP.PrS.PHF19 | Expresses human PHF19 in insect cells, , under a C3-cleavable (PreScission Protease) N-terminal hexahistidine-MBP tag. |
| 125169 | pFB1.HMBP.PrS.MTF2 | Expresses human MTF2 in insect cells, under a C3-cleavable (PreScission Protease) N-terminal hexahistidine-MBP tag. |
| 125170 | pFB1.HMBP.PrS.EPOP | Expresses human EPOP in insect cells, under a C3-cleavable (PreScission Protease) N-terminal hexahistidine-MBP tag. |
| 125171 | pFBOH-MHL.EZH2 | Expresses human EZH2 in insect cells, under a TEV-cleavable N-terminal polyhistidine tag. |
| 125172 | pFBOH-MHL.SUZ12 | Expresses human SUZ12 in insect cells, under a TEV-cleavable N-terminal polyhistidine tag. |
| 125173 | pFBOH-MHL.RBBP4 | Expresses human RBBP4 in insect cells, under a TEV-cleavable N-terminal polyhistidine tag. |
| 125174 | pFBOH-MHL.EED | Expresses human EED in insect cells, under a TEV-cleavable N-terminal polyhistidine tag. |