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The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms.
Garvin AJ, Walker AK, Densham RM, Chauhan AS, Stone HR, Mackay HL, Jamshad M, Starowicz K, Daza-Martin M, Ronson GE, Lanz AJ, Beesley JF, Morris JR
Genes Dev. 2019 Mar 1;33(5-6):333-347. doi: 10.1101/gad.321125.118. Epub 2019 Feb 22. PubMed Article

Plasmids from Article

ID Plasmid Purpose
126591FLAG-SENP2 WTExpresses siRNA resistant SENP2 (WT) in mammalian cells, Dox inducible in TetR cell lines
126592FLAG-SENP2 C548AExpresses siRNA resistant SENP2 (catalytic dead) in mammalian cells, Dox inducible in TetR cell lines
126593FLAG-SENP2 NPmExpresses siRNA resistant SENP2 (nuclear pore mutant) in mammalian cells, Dox inducible in TetR cell lines
126594FLAG-SENP2 CCmExpresses siRNA resistant SENP2 (coiled-coil deletion) in mammalian cells, Dox inducible in TetR cell lines

Antibodies from Article