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The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A.

Rivero-Rios P, Romo-Lozano M, Madero-Perez J, Thomas AP, Biosa A, Greggio E, Hilfiker S
J Biol Chem. 2019 Mar 29;294(13):4738-4758. doi: 10.1074/jbc.RA118.005008. Epub 2019 Feb 1. (Link opens in a new window) PubMed (Link opens in a new window) Article

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