LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy.
Padman BS, Nguyen TN, Uoselis L, Skulsuppaisarn M, Nguyen LK, Lazarou M
Nat Commun. 2019 Jan 24;10(1):408. doi: 10.1038/s41467-019-08335-6. PubMed Article
Padman BS, Nguyen TN, Uoselis L, Skulsuppaisarn M, Nguyen LK, Lazarou M
Nat Commun. 2019 Jan 24;10(1):408. doi: 10.1038/s41467-019-08335-6. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 119681 | pBMN mEGFP-OPTN(F178A) | For mammalian expression of LIR mutant OPTN |
| 119682 | pBMN mEGFP-NDP52(V136S) | For mammalian expression of LIR mutant NDP52 |
| 119683 | pBMN mCherry-OPTN(D474N) | For mammalian expression of UBD mutant OPTN |
| 119684 | pBMN mCherry-OPTN(F178A/D474N) | For mammalian expression of LIR/UBD double mutant OPTN |
| 119685 | pBMN mCherry-NDP52(C443K) | For mammalian expression of UBD mutant NDP52 |
| 119686 | pBMN mCherry-NDP52(V136S/C443K) | For mammalian expression of LIR/UBD double mutant NDP52 |
| 119687 | pBMN mCherry-p62(ΔUBD) | For mammalian expression of p62 without its UBD |
| 119688 | pBMN mCherry-p62(W340A/ΔUBD) | For mammalian expression of LIR mutant p62 without its UBD |
| 119689 | pBMN mCherry-TAX1BP1(ΔUBD) | For mammalian expression of TAX1BP1 without its UBD |
| 119690 | pBMN mCherry-TAX1BP1(V142S/ΔUBD) | For mammalian expression of LIR mutant TAX1BP1 without its UBD |
| 119691 | pBMN mCherry-NBR1(ΔUBD) | For mammalian expression of NBR1 without its UBD |
| 119692 | pBMN mCherry-NBR1(F562A/Y731A/ΔUBD) | For mammalian expression of LIR double mutant NBR1 without its UBD |
| 119693 | pBMN iRFP670-OPTN(D474N) | For mammalian expression of iRFP-tagged UBD mutant OPTN |
| 119694 | pBMN iRFP670-OPTN(F178A/D474N) | For mammalian expression of iRFP-tagged LIR/UBD double mutant OPTN |
| 119695 | pBMN iRFP670-NDP52(C443K) | For mammalian expression of iRFP-tagged UBD mutant NDP52 |
| 119696 | pBMN iRFP670-NDP52(V136S/C443K) | For mammalian expression of iRFP-tagged LIR/UBD double mutant NDP52 |