GPN does not release lysosomal Ca(2+) but evokes Ca(2+) release from the ER by increasing the cytosolic pH independently of cathepsin C.

Atakpa P, van Marrewijk LM, Apta-Smith M, Chakraborty S, Taylor CW
J Cell Sci. 2019 Feb 1;132(3). pii: jcs.223883. doi: 10.1242/jcs.223883. PubMed Article

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