The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1.

Menzies SA, Volkmar N, van den Boomen DJ, Timms RT, Dickson AS, Nathan JA, Lehner PJ
Elife. 2018 Dec 13;7. pii: 40009. doi: 10.7554/eLife.40009. PubMed Article

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