Clotrimazole inhibits the Wnt/beta-catenin pathway by activating two eIF2alpha kinases: The heme-regulated translational inhibitor and the double-stranded RNA-induced protein kinase.
Yonezawa H, Ogawa M, Katayama S, Shimizu Y, Omori N, Oku Y, Sakyo T, Uehara Y, Nishiya N
Biochem Biophys Res Commun. 2018 Nov 17;506(1):183-188. doi: 10.1016/j.bbrc.2018.10.053. Epub 2018 Oct 17.
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