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An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer.
Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, Ge JY, Root DE, Zhao JJ, Brooks AN, Weinberg RA, Hahn WC
Elife. 2018 Jul 30;7. pii: 37184. doi: 10.7554/eLife.37184. PubMed

Plasmids from Article

ID Plasmid Purpose
115439pLX317-EGFPConstitutive lentiviral expression
115440pLX317-hcREDConstitutive lentiviral expression
115441pLX317-QKIConstitutive lentiviral expression
115442pLX317-RBFOX1Constitutive lentiviral expression
115443pLX317-MBNL1Constitutive lentiviral expression
115444pLX317-MBNL2Constitutive lentiviral expression
115445pLX317-CELF4Constitutive lentiviral expression
115446pLX317-SNAI1Constitutive lentiviral expression
115449pXPR_BRD003-sgQKI-2201Constitutive lentiviral expression
115450pXPR_BRD003-sgQKI-2204Constitutive lentiviral expression
115451pXPR_BRD003-sgRBFOX1-2083Constitutive lentiviral expression
115452pXPR_BRD003-sgRBFOX1-2098Constitutive lentiviral expression
115453pXPR_BRD003-sgSNAI1-2097Constitutive lentiviral expression
115454pLKO.1-shLacZ-1735Constitutive lentiviral expression
115455pLKO.1-shQKI-3371Constitutive lentiviral expression
115456pLKO.1-shQKI-3373Constitutive lentiviral expression
115457pLKO.1-shRBFOX1-3260Constitutive lentiviral expression
115458pLKO.1-shRBFOX1-3261Constitutive lentiviral expression
115459pLKO.1-shMBNL1-3964Constitutive lentiviral expression
115460pLKO.1-shMBNL1-9155Constitutive lentiviral expression
115461pLKO.1-shMBNL2-3712Constitutive lentiviral expression
115462pLKO.1-shMBNL2-1082Constitutive lentiviral expression
115463pLKO.1-shMBNL3-0455Constitutive lentiviral expression
115464pLKO.1-shMBNL3-9465Constitutive lentiviral expression
115465pLKO.1-shCELF4-4404Constitutive lentiviral expression
115466pLKO.1-shCELF4-4405Constitutive lentiviral expression
115467pLKO.1-shSNAI1Constitutive lentiviral expression
119873pXPR_sgFLNB-SK2gRNA expression vector
119874pXPR_sgFLNB-SK4gRNA expression vector
119875pXPR_sgGFP3gRNA expression vector
119876pXPR_sgGFP4gRNA expression vector

Antibodies from Article