Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
Menade M, Kozlov G, Trempe JF, Pande H, Shenker S, Wickremasinghe S, Li X, Hojjat H, Dicaire MJ, Brais B, McPherson PS, Wong MJH, Young JC, Gehring K
J Biol Chem. 2018 Aug 17;293(33):12832-12842. doi: 10.1074/jbc.RA118.003939. Epub 2018 Jun 26.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 75297 | pGEX6P1-sr1(SIRPT1) | Expresses Sacsin sr1 (SIRPT1 repeat) domain (84-339) in fusion with GST (bacterial) |
| 75298 | pGEX6P1-Ubl-sr1(SIRPT1) | Expresses Sacsin Ubl-sr1 (SIRPT1 repeat) domain (1-339) in fusion with GST (bacterial) |
| 78712 | pGEX6P1-Ubl | Expresses Sacsin Ubl- domain (2-85) in fusion with GST (bacterial) |