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Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2.

Ishida S, Akiyama H, Umezawa Y, Okada K, Nogami A, Oshikawa G, Nagao T, Miura O
Oncotarget. 2018 Jun 1;9(42):26834-26851. doi: 10.18632/oncotarget.25515. eCollection 2018 Jun 1. (Link opens in a new window) PubMed (Link opens in a new window) Article

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