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The proinflammatory protein HMGB1 is a substrate of transglutaminase-2 and forms high-molecular weight complexes with autoantigens.

Willis WL, Wang L, Wada TT, Gardner M, Abdouni O, Hampton J, Valiente G, Young N, Ardoin S, Agarwal S, Freitas MA, Wu LC, Jarjour WN
J Biol Chem. 2018 Jun 1;293(22):8394-8409. doi: 10.1074/jbc.RA117.001078. Epub 2018 Apr 4. (Link opens in a new window) PubMed (Link opens in a new window) Article

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