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Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.

Zyryanova AF, Weis F, Faille A, Alard AA, Crespillo-Casado A, Sekine Y, Harding HP, Allen F, Parts L, Fromont C, Fischer PM, Warren AJ, Ron D
Science. 2018 Mar 30;359(6383):1533-1536. doi: 10.1126/science.aar5129. (Link opens in a new window) PubMed (Link opens in a new window) Article

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