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Small-molecules that bind to the ubiquitin-binding motif of REV1 inhibit REV1 interaction with K164-monoubiquitinated PCNA and suppress DNA damage tolerance.

Vanarotti M, Evison BJ, Actis ML, Inoue A, McDonald ET, Shao Y, Heath RJ, Fujii N
Bioorg Med Chem. 2018 May 15;26(9):2345-2353. doi: 10.1016/j.bmc.2018.03.028. Epub 2018 Mar 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

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