A positive feedback loop between IL-1beta, LPS and NEU1 may promote atherosclerosis by enhancing a pro-inflammatory state in monocytes and macrophages.

Sieve I, Ricke-Hoch M, Kasten M, Battmer K, Stapel B, Falk CS, Leisegang MS, Haverich A, Scherr M, Hilfiker-Kleiner D
Vascul Pharmacol. 2018 Apr;103-105:16-28. doi: 10.1016/j.vph.2018.01.005. Epub 2018 Jan 31. PubMed Article

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