RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.
Qutob N, Masuho I, Alon M, Emmanuel R, Cohen I, Di Pizio A, Madore J, Elkahloun A, Ziv T, Levy R, Gartner JJ, Hill VK, Lin JC, Hevroni Y, Greenberg P, Brodezki A, Rosenberg SA, Kosloff M, Hayward NK, Admon A, Niv MY, Scolyer RA, Martemyanov KA, Samuels Y
Sci Rep. 2018 Jan 12;8(1):653. doi: 10.1038/s41598-017-18851-4.
(Link opens in a new window)
PubMed
Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
113728 | pCDF1-MCS2-EF1-Puro-RGS7 | Express RGS7 in mamalian cells |
113729 | pCDF1-MCS2-EF1-Puro-RGS7-R44C | Express mutant RGS7- R44C- in mamalian cells |
113730 | pCDF1-MCS2-EF1-Puro-RGS7-R44C+V56C | Express double mutant RGS7- R44C+V65C in mamalian cells |
113731 | pCDF1-MCS2-EF1-Puro-RGS7-E383K | Express mutant RGS7- E383K- in mamalian cells |