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RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.

Qutob N, Masuho I, Alon M, Emmanuel R, Cohen I, Di Pizio A, Madore J, Elkahloun A, Ziv T, Levy R, Gartner JJ, Hill VK, Lin JC, Hevroni Y, Greenberg P, Brodezki A, Rosenberg SA, Kosloff M, Hayward NK, Admon A, Niv MY, Scolyer RA, Martemyanov KA, Samuels Y
Sci Rep. 2018 Jan 12;8(1):653. doi: 10.1038/s41598-017-18851-4. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
113728pCDF1-MCS2-EF1-Puro-RGS7Express RGS7 in mamalian cells
113729pCDF1-MCS2-EF1-Puro-RGS7-R44CExpress mutant RGS7- R44C- in mamalian cells
113730pCDF1-MCS2-EF1-Puro-RGS7-R44C+V56CExpress double mutant RGS7- R44C+V65C in mamalian cells
113731pCDF1-MCS2-EF1-Puro-RGS7-E383KExpress mutant RGS7- E383K- in mamalian cells

Antibodies from Article