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NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis.
Alvarez SW, Sviderskiy VO, Terzi EM, Papagiannakopoulos T, Moreira AL, Adams S, Sabatini DM, Birsoy K, Possemato R
Nature. 2017 Nov 22. doi: 10.1038/nature24637.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
102963pLKO.1P shNFS1_1Suppression of NFS1
102964pLKO.1P shNFS1_2Suppression of NFS1
102965pLKO.1P shNFS1_3Suppression of NFS1
102966pLKO.1P shNFS1_4Suppression of NFS1
102967pLKO.1P shNfs1Suppression of mNfs1
102968pLKO.1P shABCB7_1Suppression of ABCB7
102969pLKO.1P shABCB7_2Suppression of ABCB7
102970pLKO.1P shFXN_1Suppression of FXN
102971pLKO.1P shFXN_2Suppression of FXN
102972pLKO.1P shISCUSuppression of ISCU
102973pLKO.1P shMOCS3_1Suppression of MOCS3
102974pLKO.1P shMOCS3_2Suppression of MOCS3
102975pLKO.1P shSOD1Suppression of SOD1
102976pLKO.1P shSOD2Suppression of SOD2
102977pBabe hygro NFS1Expression of NFS1
102978pBabe hygro NFS1 CDExpression of NFS1 C381A mutant
102979pLENTICRISPR sgNFS1Cutting NFS1 genomic locus

Antibodies from Article