A two-amino-acid substitution in the transcription factor RORgammat disrupts its function in TH17 differentiation but not in thymocyte development.

He Z, Ma J, Wang R, Zhang J, Huang Z, Wang F, Sen S, Rothenberg EV, Sun Z
Nat Immunol. 2017 Oct;18(10):1128-1138. doi: 10.1038/ni.3832. Epub 2017 Aug 28. PubMed Article

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