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Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.
Geng J, Ito Y, Shi L, Amin P, Chu J, Ouchida AT, Mookhtiar AK, Zhao H, Xu D, Shan B, Najafov A, Gao G, Akira S, Yuan J
Nat Commun. 2017 Aug 25;8(1):359. doi: 10.1038/s41467-017-00406-w. PubMed

Plasmids from Article

ID Plasmid Purpose
115339pcDNA3.1-Flag-mRIPK1-S321AMammalian expression of Flag-mRIPK1-S321A
115340pcDNA3.1-Flag-mRIPK1-S321EMammalian expression of Flag-mRIPK1-S321E
115341pAAV2-TBG-FLAG-mRIPK1Liver-specific adeno-associated viral delivery and mammalian expression of Flag-mRIPK1
115342pAAV2-TBG-FLAG-mRIPK1-S321ALiver-specific adeno-associated viral delivery and mammalian expression of Flag-mRIPK1-S321A
115343pAAV2-TBG-FLAG-mRIPK1-S321ELiver-specific adeno-associated viral delivery and mammalian expression of Flag-mRIPK1-S321E

Antibodies from Article