Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.
Monahan Z, Ryan VH, Janke AM, Burke KA, Rhoads SN, Zerze GH, O'Meally R, Dignon GL, Conicella AE, Zheng W, Best RB, Cole RN, Mittal J, Shewmaker F, Fawzi NL
EMBO J. 2017 Aug 8. pii: e201696394. doi: 10.15252/embj.201696394.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 98652 | MBP-FUS_FL_12E | Expresses MBP-tagged full length phosphomimetic FUS |
| 98653 | MBP-FUS_LC_WT | Expresses MBP-tagged FUS AA 1-163 |
| 98654 | MBP-FUS_LC_12E | Expresses MBP-tagged phosphomimetic FUS AA 1-163 |
| 98655 | MBP-FUS_FL_6E | Expresses MBP-tagged full length phosphomimetic FUS |