Reactivation of the p90RSK-CDC25C pathway leads to bypass of the ganetespib induced G2/M arrest and mediates acquired resistance to ganetespib in KRAS mutant NSCLC.
Chatterjee S, Huang EH, Christie I, Burns TF
Mol Cancer Ther. 2017 May 31. pii: molcanther.0114.2017. doi: 10.1158/1535-7163.MCT-17-0114.
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