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Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability.

Utani K, Fu H, Jang SM, Marks AB, Smith OK, Zhang Y, Redon CE, Shimizu N, Aladjem MI
Nucleic Acids Res. 2017 May 26. doi: 10.1093/nar/gkx468. (Link opens in a new window) PubMed (Link opens in a new window) Article

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