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Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes.
Cerboni S, Jeremiah N, Gentili M, Gehrmann U, Conrad C, Stolzenberg MC, Picard C, Neven B, Fischer A, Amigorena S, Rieux-Laucat F, Manel N
J Exp Med. 2017 Jun 5;214(6):1769-1785. doi: 10.1084/jem.20161674. Epub 2017 May 8. PubMed Article

Plasmids from Article

ID Plasmid Purpose
102585pTRIP-SFFV-mtagBFP-2AControl lentivector. Coexpression of mTagBFP and gene of interest from SFFV promoter
102586pTRIP-SFFV-mtagBFP-2A STINGLentivector to express STING and mTagBFP
102587pTRIP-SFFV-mtagBFP-2A STINGHAQ Lentivector to express STING HAQ and mTagBFP
102588pTRIP-SFFV-mtagBFP-2A STING-342STOPLentivector to express STING delta 342 and mTagBFP
102589pTRIP-SFFV-mtagBFP-2A STING-354STOPLentivector to express STING delta 354 and mTagBFP
102590pTRIP-SFFV-mtagBFP-2A STING 368STOPLentivector to express STING delta 368 and mTagBFP
102591pTRIP-SFFV-mtagBFP-2A STING V155MLentivector to express STING V155M and mTagBFP
102592pTRIP-SFFV-mtagBFP-2A STINGHAQ V155MLentivector to express STING V155M HAQ and mTagBFP
102593pTRIP-SFFV-mtagBFP-2A STING-V155M S366ALentivector to express STING V155M S366A and mTagBFP
102594pTRIP-SFFV-mtagBFP-2A STING V155M 342STOPLentivector to express STING V155M delta 342 and mTagBFP
102595pTRIP-SFFV-mtagBFP-2A STING V155M 354STOPLentivector to express STING V155M delta 354 and mTagBFP
102596pTRIP-SFFV-mtagBFP-2A STING V155M 368STOPLentivector to express STING V155M delta 368 and mTagBFP
102598pMSCV-hygro-STINGExpress STING for IFN-beta luciferase reporter assay.
102599pMSCV-hygro-STING V155MExpress STING V155M for IFN-beta Luciferase reporter assay.
102600pMSCV-hygro-STING HAQExpress STING HAQ for IFN-beta Luciferase reporter assay.
102601pMSCV-hygro-STING HAQ+V155MExpress STING V55M HAQ for IFN-beta Luciferase reporter assay.
127640pLentiCRISPRv2-STING_gRNA3Knock-out of human STING

Antibodies from Article