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Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein.

Dong D, Guo M, Wang S, Zhu Y, Wang S, Xiong Z, Yang J, Xu Z, Huang Z
Nature. 2017 Jun 15;546(7658):436-439. doi: 10.1038/nature22377. Epub 2017 Apr 27. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
101042AcrIIA2Anti-CRISPRprotein which inhibit SpyCas9 and LmoCas9 activity.
101043AcrIIA4Anti-CRISPRprotein which inhibit SpyCas9 and LmoCas9 activity.
101044SpyCas9(WT)Express Streptococcus pyogenes Cas9

Antibodies from Article