KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
Wolfson RL, Chantranupong L, Wyant GA, Gu X, Orozco JM, Shen K, Condon KJ, Petri S, Kedir J, Scaria SM, Abu-Remaileh M, Frankel WN, Sabatini DM
Nature. 2017 Feb 15. doi: 10.1038/nature21423. PubMed Article
Wolfson RL, Chantranupong L, Wyant GA, Gu X, Orozco JM, Shen K, Condon KJ, Petri S, Kedir J, Scaria SM, Abu-Remaileh M, Frankel WN, Sabatini DM
Nature. 2017 Feb 15. doi: 10.1038/nature21423. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 87034 | pRK5-FLAG-SZT2 | mammalian expression of SZT2 |
| 87035 | pRK5-HA-SZT2 | mammalian expression of SZT2 |
| 87036 | pRK5-FLAG-SZT2 1-1021 | mammalian expression of SZT2 fragment |
| 87037 | pRK5-HA-SZT2 1-1021 | mammalian expression of SZT2 fragment |
| 87039 | pRK5-FLAG-SZT2 2241-end | mammalian expression of SZT2 fragment |
| 87040 | pRK5-HA-SZT2 2241-end | mammalian expression of SZT2 fragment |
| 87041 | pRK5-FLAG-KPTN | mammalian expression of KPTN |
| 87042 | pRK5-HA-KPTN | mammalian expression of KPTN |
| 87043 | pRK5-MYC-KPTN | mammalian expression of KPTN |
| 87044 | pRK5-FLAG-ITFG2 | mammalian expression of ITFG2 |
| 87045 | pRK5-HA-ITFG2 | mammalian expression of ITFG2 |
| 87046 | pRK5-MYC-ITFG2 | mammalian expression of ITFG2 |
| 87047 | pRK5-FLAG-C12orf66 | mammalian expression of C12orf66 |
| 87048 | pRK5-HA-C12orf66 | mammalian expression of C12orf66 |
| 87049 | plc242-GFP-ITFG2 | mammalian expression of ITFG2 |
| 87050 | plc242-GFP-WDR24 | mammalian expression of WDR24 |
| 87051 | plc242-GFP-Nprl2 | mammalian expression of Nprl2 |
| 87052 | KG371-GFP-mios | mammalian expression of mios |