Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.
Nguyen TN, Padman BS, Usher J, Oorschot V, Ramm G, Lazarou M
J Cell Biol. 2016 Dec 19;215(6):857-874. Epub 2016 Nov 18. PubMed Article
Nguyen TN, Padman BS, Usher J, Oorschot V, Ramm G, Lazarou M
J Cell Biol. 2016 Dec 19;215(6):857-874. Epub 2016 Nov 18. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 89290 | pMX-IY LC3A | For expression of the mammalian Atg8 protein LC3A without a tag |
| 89291 | pMX-IY LC3B | For expression of the mammalian Atg8 protein LC3B without a tag |
| 89292 | pMX-IY LC3C | For expression of the mammalian Atg8 protein LC3C without a tag |
| 89293 | pBMN GBRP | For expression of the mammalian Atg8 protein GABARAP without a tag |
| 89294 | pMX-IY GBRPL1 | For expression of the mammalian Atg8 protein GABARAPL1 without a tag |
| 89295 | pMX-IY GBRPL2 | For expression of the mammalian Atg8 protein GABARAPL2 without a tag |
| 89296 | pBMN HA-GBRP | For expression of the mammalian Atg8 protein GABARAP tagged with HA |
| 89297 | pMX-IY HA-GBRPL1 | For expression of the mammalian Atg8 protein GABARAPL1 tagged with HA |
| 89298 | pMX-IY HA-GBRPL2 | For expression of the mammalian Atg8 protein GABARAPL2 tagged with HA |
| 89299 | pBMN Parkin | For expression of untagged Parkin |
| 89300 | pBMN PLEKHM1-HA | For expression of PLEKHM1 tagged with HA |