Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1.
Rojansky R, Cha MY, Chan DC
Elife. 2016 Nov 17;5. pii: e17896. doi: 10.7554/eLife.17896. PubMed Article
Rojansky R, Cha MY, Chan DC
Elife. 2016 Nov 17;5. pii: e17896. doi: 10.7554/eLife.17896. PubMed Article
Plasmids from Article
ID | Plasmid | Purpose | |
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78518 | pBABEpuro mTurquoise2 LC3B | Fluorescent reporter for LC3B visualization |
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78520 | pCLBW cox8 EGFP mCherry | Fluorescent mitophagy reporter |
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78522 | pFUChW nontargeting shRNA | Lentiviral vector encoding shRNA and mCherry reporter |
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78523 | pFUChW Parkin shRNA Mul1 shRNA | Lentiviral vector encoding two shRNAs and mCherry reporter |
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