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Genome editing using CRISPR-Cas9 to create the HPFH genotype in HSPCs: An approach for treating sickle cell disease and beta-thalassemia.

Ye L, Wang J, Tan Y, Beyer AI, Xie F, Muench MO, Kan YW
Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):10661-5. doi: 10.1073/pnas.1612075113. Epub 2016 Sep 6. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
84039pX601-mCherryStaphylococcus aureus (SaCas9) conjugated with mCherry
84040pX601-GFPStaphylococcus aureus (SaCas9) conjugated with GFP

Antibodies from Article