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The T300A Crohn's disease risk polymorphism impairs function of the WD40 domain of ATG16L1.

Boada-Romero E, Serramito-Gomez I, Sacristan MP, Boone DL, Xavier RJ, Pimentel-Muinos FX
Nat Commun. 2016 Jun 8;7:11821. doi: 10.1038/ncomms11821. (Link opens in a new window) PubMed (Link opens in a new window) Article

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