Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL.
McComb S, Aguade-Gorgorio J, Harder L, Marovca B, Cario G, Eckert C, Schrappe M, Stanulla M, von Stackelberg A, Bourquin JP, Bornhauser BC
Sci Transl Med. 2016 May 18;8(339):339ra70. doi: 10.1126/scitranslmed.aad2986. PubMed Article
McComb S, Aguade-Gorgorio J, Harder L, Marovca B, Cario G, Eckert C, Schrappe M, Stanulla M, von Stackelberg A, Bourquin JP, Bornhauser BC
Sci Transl Med. 2016 May 18;8(339):339ra70. doi: 10.1126/scitranslmed.aad2986. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 75159 | pLentiCRISPR-EGFP | Derived from LentiCRISPR v1 but expresses EGFP instead of puromycin resistance |
| 75160 | pLentiCRISPR-tagBFP | Derived from LentiCRISPR v1 but expresses tagBFP instead of puromycin resistance |
| 75161 | pLentiCRISPR-mCherry | Derived from LentiCRISPR v1 but expresses mCherry instead of puromycin resistance. 3rd generation. |
| 75162 | pLentiCRISPR-RFP657 | Derived from LentiCRISPR v1 but expresses RFP657 instead of puromycin resistance |
| 75163 | pLC-EGFP-RIP1 | LentiCRISPR-EGFP with sgRNA targeting human RIPk1 |
| 75164 | pLC-RFP657-CASP8 | LentiCRISPR-RFP657 with sgRNA targeting human Caspase-8 |
| 75165 | pLC-EGFP-RIP3 | LentiCRISPR-EGFP with sgRNA targeting human RIP3 |
| 75166 | pLC-BFP-FADD | LentiCRISPR-BFP with sgRNA targeting human FADD |
| 75167 | pLC-mCherry-MLKL | LentiCRISPR-mCherry with sgRNA targeting human MLKL |