Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites.
Breda C, Sathyasaikumar KV, Sograte Idrissi S, Notarangelo FM, Estranero JG, Moore GG, Green EW, Kyriacou CP, Schwarcz R, Giorgini F
Proc Natl Acad Sci U S A. 2016 May 10;113(19):5435-40. doi: 10.1073/pnas.1604453113. Epub 2016 Apr 25.
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