Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis.
Lin NY, Distler A, Beyer C, Philipi-Schobinger A, Breda S, Dees C, Stock M, Tomcik M, Niemeier A, Dell'Accio F, Gelse K, Mattson MP, Schett G, Distler JH
Ann Rheum Dis. 2016 Feb 5. pii: annrheumdis-2015-208420. doi: 10.1136/annrheumdis-2015-208420.
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