The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice.
Ismail IH, Gagne JP, Genois MM, Strickfaden H, McDonald D, Xu Z, Poirier GG, Masson JY, Hendzel MJ
Nat Cell Biol. 2015 Nov;17(11):1446-57. doi: 10.1038/ncb3259. Epub 2015 Oct 26. PubMed Article
Ismail IH, Gagne JP, Genois MM, Strickfaden H, McDonald D, Xu Z, Poirier GG, Masson JY, Hendzel MJ
Nat Cell Biol. 2015 Nov;17(11):1446-57. doi: 10.1038/ncb3259. Epub 2015 Oct 26. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 78920 | pEGFP-RNF138-WT | Mammalian expression of RNF138 with an EGFP fusion |
| 78921 | pEGFP-RNF138-delta 18-58 | Mammalian expression of RNF138 with delta 18-58 and an EGFP fusion |
| 78922 | pEGFP-RNF138-delta 86-105 | Mammalian expression of RNF138 with delta 86-105 and an EGFP fusion |
| 78923 | pEGFP-RNF138-delta 158-180 | Mammalian expression of RNF138 with delta 158-180 and an EGFP fusion |
| 78924 | pEGFP-RNF138-delta 189-215 | Mammalian expression of RNF138 with delta 189-215 and an EGFP fusion |