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The C. elegans Crumbs family contains a CRB3 homolog and is not essential for viability.

Waaijers S, Ramalho JJ, Koorman T, Kruse E, Boxem M
Biol Open. 2015 Feb 6;4(3):276-84. doi: 10.1242/bio.201410744. (Link opens in a new window) PubMed (Link opens in a new window) Article

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