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Glutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagy.

Van Laar VS, Roy N, Liu A, Rajprohat S, Arnold B, Dukes AA, Holbein CD, Berman SB
Neurobiol Dis. 2015 Feb;74:180-93. doi: 10.1016/j.nbd.2014.11.015. Epub 2014 Dec 3. (Link opens in a new window) PubMed (Link opens in a new window) Article

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