Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1alpha by inhibiting prolyl-4-hydroxylase PHD2.
Hou P, Kuo CY, Cheng CT, Liou JP, Ann DK, Chen Q
PLoS One. 2014 Nov 24;9(11):e113865. doi: 10.1371/journal.pone.0113865. eCollection 2014.
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