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IFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modifications.

Johnson KE, Bottero V, Flaherty S, Dutta S, Singh VV, Chandran B
PLoS Pathog. 2014 Nov 6;10(11):e1004503. doi: 10.1371/journal.ppat.1004503. eCollection 2014 Nov. (Link opens in a new window) PubMed (Link opens in a new window) Article

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